An Emergin Area of Targeted Cancer Therapy: DNA Damagae Repair and Signaling Pathways

Lee Zou△

MGH Cancer Center

Targeting the ATR checkpoint in cancer therapy  

Shan Zha△*

Columbia University

Precision medicine with old friends –structural function of ATM and ATR

Junjie Chen

MD Anderson Cancer Center

Proteomic analysis of DNA replication and replication checkpoint control

Lei Li

MD Anderson Cancer Center

Transcription-aided suicide - Molecular Pathology of Fanconi anemia.

Zhiyuan Shen

Robert Wood Johnson Medical School

DNA replication fork stability protected by BCCIP and its fingerprints in tumorigenesis

Li Lan

Hillman Cancer Center

Introducing DNA damage at the end of chromosomes and its effect in cancers

Dongyi Xu

Peking University

To be added soon. Rif1 promotes stalled replication fork restart

Cancer metabolism and beyond

Hsing-Jien Kung△

NHRI and NTHU, TW

Targeting tumor metabolism and mitochondria: the histone demethylase connection

Wen-Ching Wang

National Tsing Hua University, TW

 

Jing Chen

Emory University School of Medicine

Diet-fueled metabolic rewiring in human cancer

David Ann

Beckman Research Institute, City of Hope

Metabolic Stress-Induced Mitochondrial Reprograming

Boyi Gan

MD Anderson Cancer Center

Energy Sensing and Metabolism in Cancer

Zhimin Lu△

MD Anderson Cancer Center

Protein kinase activity of metabolic enzymes

Mechanisms of Genomic Instability Syndromes: From Genetics To Genomics.

Wei Yang△*

National Institute of Diabetes and Digestive and Kidney Diseases

 

Xiaochun Yu△*

Beckman Research Institute, City of Hope

Novel therapeutic targets for Genomic Instability Syndromes (backup speaker)

Xiaolan Zhao△*

Memorial Sloan Kettering Cancer Center

Mechanisms of the Smc5/6 complex that prevents new types of genomic instability syndromes

Binghui Shen

City of Hope

Guarding genomic DNA by FEN1 nuclease

Guo-Min Li

Tsinghua University

Mechanism of repeat instability-caused neurodegenerative disorders

Feng Qiao

University of California

Targeting the ends of the chromosomes: from new mechanisms to new therapeutics

Xiaolan Zhao

Memorial Sloan Kettering Cancer Center

Mechanisms of the Smc5/6 complex that prevents new types of genomic instability syndromes

Huang Jun

Zhejiang University

The role of CAR1 in genome stability protection

Nuclear Receptor Function and Diseases

Sophia Y. Tsai△*

Baylor College of Medicine

 

Ming-Jer Tsai△*

Baylor College of Medicine

 

Jianming Xu

Baylor College of Medicine

Nuclear receptor coregulator Ncoa6 regulates prostate epithelial differentiation & carcinogenesis

Hongwu Chen

School of Medicine UCDMC Research III

Nuclear receptor RORs as novel therapeutic targets in prostate cancer

Shih-Chieh (Jay) Lin

National Cheng Kung University

The role of COUP-TFII-miR-21-YAP1 regulation axis in enzalutamide-resistant prostate cancer

Hao Ying

Institute for Nutritional Sciences

Thyroid hormone regulated-microRNA in cholesterol metabolism

Sheue-yann Cheng

National Cancer Institute

Defective Erythropoiesis Caused by Mutations of the Thyroid Hormone Receptor Alpha Gene

Recent Advances in Cancer Research

Burton B. Yang△

Sunnybrook Health Sciences Centre

Roles of circular RNA in breast cancer development

Shi-Mei Zhuang

Sun Yat-Sen University

non-coding RNA in the development of hepatocellular carcinoma

Jin-Xin Bei

Sun Yat-Sen University Cancer Center

The genetic landscape of EBV-related Malignancies

Benjamin K. Tsang

University of Ottawa

Gelsolin and chemoresistant ovarian cancer: from basic to translational research

Chun Peng△*

York University, Toronto

Cyclin G2 suppresses ovarian cancer metastasis

New Concepts of Radiation Biology: its implication in human health and cancer therapy

Fen Xia△*

University of Arkansas College of Medicine

 

Zhenkun Lou△*

Mayo Clinic College of Medicine & Science

 

Tom Hei

Columbia University Medical Center

The New Radiobiology: Extranuclear and Extracellular Effects of Ionizing Radiation

Zhimin Yuan,

Harvard University School of Public Health

Low doses of irradiation induce a protective metabolic response

Ya Wang

Emory University

Difference in repair of low and high-LET radiation-induced DNA damage

Jian Yuan

Tongji University School of Medicine

The role of deubiquitinase in radioresistance

Chuan-Yuan Li

Duke University Medical Center

Caspases, DNA repair, and stemness of cancer cells

Retinal Function and Diseases

Ting Xie△*

Stowers Institute for Medical Research

Anterior segment development and potential implications in glaucoma pathogenesis

Wei Li△*

National Institutes of Health

Retinal adaptations to metabolic challenges

Zhigang He

Boston Children's Hospital

Retinal ganglion cell axon regeneration

Ching-Hwa Sung

Weill Medical College of Cornell University

Photoreceptor development, stem cell, and retinal degenerative diseases

Tian Xue

University of Science & Technology of China

Function of non-image-forming retinal ganglion cells

Energy and Glucose Homeostasis: A Symphony by the Neuro-Immuno-Endocrine Orchestra

Yong Xu△

Baylor College of Medicine

Hypothalamic steroid receptor coactivator-1 and energy homeostasis

Qin Yang

University of California

Epigenetic regulation of insulin resistance and energy expenditure

Qingchun Tong

University of Texas McGovern Medical School

Red blood cell β-adrenergic receptors contribute to diet-induced energy expenditure by
increasing O2 supply

Feng Liu△*

Department of Pharmacology, UTHSCSA

The roles of ER and mitochondrial stress in insulin resistance and type 2 diabetes

Wenxian Fu

University of California

Novel role of macrophages in islet inflammation of type 1 and type 2 diabetes.

 New Insights on Alcoholic and Nonalcoholic Liver Diseases: Organ Crosstalk and Mechanisms

Min You△

Northeast Ohio Medical University

Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and
Ameliorates Ethanol-Induced Liver Injury in Mice.

Jun Sun△*

University of Illinois at
Chicago

Novel roles of vitamin D receptor in mediating gut-liver axis and microbiota

Xudong Hu

Shanghai University of Tranditional
Chinese Medicine

MitoNEET Deficiency Alleviates Experimental Alcoholic Steatohepatitis in Mice by
Stimulating Endocrine Adiponectin-FGF15 Axis

Chaohui Yu

Zhejiang University

Omics in Nonalcoholic fatty liver disease

Zhenyuan Song

University of Illinois Medical Center

SIRT3-mediated autophagy suppression dictates lipotoxicity in hepatocytes

Metabolic risk factors and liver cancer

Bangyan L Stiles△*

Keck School of Medicine

Steatosis induces Wnt to promote liver cancer.

Yingzi Yang△*

Harvard School of Dental Medicine

Interacting network of Wnt/β-catenin, Notch and Hippo signaling regulates liver tumor
formation.

Wendong Huang

Beckman Research Institute of City of Hope

CAMKII as a link between liver metabolism and cancer development

Yinying Lu

302 Military Hospital of China

Insulin Resistance, Diabetes and HBV-related HCC

Jiayou Wang

Guangzhou University of
Chinese Medicine

Splicing Regulator Slu7 Uncouples Steatosis and Liver Injury in Ethanol-Fed Mice

p53, Metabolism, and Cancer

Zhaohui Feng△

State University of New Jersey

Glucose metabolism regulation by p53 and its tumor-associated mutants

Wei Gu

Columbia University

p53 engages multiple metabolic pathways with ferroptosis for tumor suppression

Hua Lu△*

Tulane University School of Medicine

Dual defects of MDM2-MDMX-p53 signaling in cancer metabolism and development.

Zhimin Yuan

Harvard Chan School of Public Health

p53 regulates metabolism in a transcription-independent mechanism

Yanping Zhang

Department of Radiation Oncology

The role of MDM2-p53 loop in cancer metabolism and biology.

Wenwei Hu

State University of New Jersey

Mutant p53 gain of function in cancer

Communication between transcription and histone regulation

Dong Wang△

University of California San Diego

Mechanism of Pol II Transcription Elongation Control and Lesion Recognition

Yan Jessie Zhang△

University of Texas at Austin

Deciphering the CTD code for eukaryotic transcription

Xin Liu

UT Southwestern Medical Center

Molecular basis of gene regulation by polycomb repressive complexes

Kai Ge

NIDDK, NIH

Enhancer chromatin modification in cell fate transition

Xiaobing Shi

M.D. Anderson Cancer Center

Reading histone code

Bing Li

UT Southwestern Medical Center at Dallas

Molecular features of travelling chromatin modifiers

Hematological malignancies

Qing Yi△*

Cleveland Clinic

Targeting Tumor and Its Microenvironment for Myeloma Therapy

B. Hilda Ye△

Albert Einstein College of Medicine

Novel Roles of STAT3 in Diffuse Large B-cell Lymphomas

Qing Yi,

Cleveland Clinic

 

B. Hilda Ye

Albert Einstein College of Medicine

 

Fenghuang Zhan

University of Iowa Carver School of Medicine

Modulation of Cellular Iron Metabolism: a New Therapeutic Strategy for Multiple Myeloma

Jing Yang

MD Anderson Cancer Center

Thymidine Phosphorylase and Myeloma-Associated Bone Disease

Jianjun Zhao

Cleveland Clinic

Functional Study Genetic Lesions in Multiple Myeloma Initiation and Progression

Cullin-RING ligase and protein neddylation in cancer biology

Yi Sun△

Zhejiang University and University of Michigan

 

Lingqiang Zhang△

Beijing Institute of Radiation Medicine

 

Yue Xiong

University of North Carolina at Chapel Hill & Fudan University

The mechanism, assembly and control of the Cullin-ROC1 family E3 ligases

Wenyi Wei

Beth Israel Deaconess Medical Center

Targeting the SCF ubiquitination pathway for cancer therapies

Pengbo Zhou

Cornell University

Physiological and pathological roles of the Cullin 4 ubiquitin ligases

Lijun Jia

Fudan University

Neddylation modification as an attractive anticancer target

Ping Wang

Tongji University

Regulation of cancer stem cells by ubiquitination

Therapeutic Resistance in Prostate Cancer

Yun Qiu△

University of Maryland School of Medicine

Epigenetic regulation and therapeutic resistance in prostate cancer

Yun-Fai Chris Lau△

University of California

The Battle of the Sexes: TSPY and TSPX Actions in AR Signaling and Prostate Cancer

Jiaoti Huang

Duke University Medical Center

Cellular heterogeneity and therapeutic resistance in prostate cancer

Haojie Huang

Mayo Clinic

Molecular subtypes of prostate cancer and therapy resistance

Jindan Yu

Northwestern University

Genetic and Epigenetic Regulation of AR signaling in Prostate Cancer

Innate Immune Responses and Inflammation

Shan-Lu Liu

Ohio State University

Novel cellular factors modulating viral infection

Pinglong Xu(徐平龙)

Zhejiang University

Dynamic regulation of cytosolic nucleic acid sensing by phosphorylation and dephosphorylation

Qing Kenneth Wang王擎△

Huazhong University of Science and Technology

Genetics basis of inflammation in coronary artery diseases

Guangxun Meng, (孟广勋)

Institut Pasteur of Shanghai, CAS

Function of the NLRP3 Inflammasome in Gut Inflammation

Tsan Sam Xiao△*

Case Western Reserve University

Molecular Mechanisms of Pyroptosis Regulation

Genomic and Nongemoic Signaling and Functions of Steroids and Their Receptors.

Yong Zhu△*

East Carolina University

To determine functions of membrane and nuclear progestin receptors during oocyte maturation,
ovulation and early development using knockout zebrafish model.

Yunbo Shi△*

National Institutes of Health

Nuclear action of TRα controls metamorphic timing and rate during Xenopus development

Bon-chu Chung

National Tsing Hua University, TW

Nongenomic Action of Neurosteroid Pregnenolone in Neurons

Victor Hsia

University of Maryland Eastern Shore

Thyroid Hormone Contributed to Herpes Viruses Gene Regulation in Neurons

Paul Yen

National University of Singapore

Thyroid Hormone Regulation of Mitophagy

Shixi Chen

Xiamen University

Functions of steroids and their receptors in male reproduction.

Xiao Fan Zhao

Shandong University

Steroid hormone 20-hydroxyecdysone via G-protein-coupled-receptor transmits signal in insect.

Novel Molecular Landscapes Leading to Prostate Cancer Progression

Wenliang Li

The University of Texas Health Science Center at Houston

Beta adrenergic signaling and GRK3 in prostate cancer progression

Yan Dong

Tulane University School of Medicine

New insights into Androgen Receptor Splice Variants in Prostate Cancer

Kexin Xu

The University of Texas Health Science Center at San Antonio

Treat prostate cancer in an EaZHy way

Jer-Tsong Hsieh△*

UT Southwestern Medical Center

Pro-metastatic effect of interferon on prostate cancer via microRNA regulation

Qi Cao△*

Houston Methodist Research Institute

A novel role for BMI1 in prostate cancer

Systemic Mechanisms of Aging

Meng Wang△

Baylor College of Medicine

Autonomous and Non-autonomous Regulation of Aging via Lysosomal Lipid Signaling

Guanghui Liu

Institute of Biophysics, CAS

Using Stem Cell and Gene Editing Techniques to Study and Treat Aging-Associated Disorders

Syliva Lee

Cornell University

Genetic and Epigenetic Determinants of Longevity in C. elegans

Weiwei Dang△

Baylor College of Medicine

Maintenance of transcription fidelity is a conserved longevity mechanism

Hao Li

University of California

Systems Biology of Cellular Aging

Genome maintenance, DNA Repair and Recombination

Robert Yu-Lin Tsai

Texas A&M University

Discovery of a new genome maintenance program in tumor progression

Shiaw-Yih (Phoebus) Lin

MD Anderson Cancer Center

Signature-guided approaches for targeting DNA damage defects

Hengyao Niu

Indiana University

Mechanisms and regulation of DNA break processing in eukaryotes

Huang-Yuan Chi△

National Taiwan University

The role of polyamines in DNA double-strand break repair

Ting-Fang Wang △*

Institute of Molecular Biology, TW

SUMO modification in DNA repair and recombination during meiosis

New Frontier of Cancer Metastasis Research: From Lab Bench to Bedside

Dihua Yu△*

MD Anderson Cancer Center

In vivo kinome screen uncovering new therapeutic targets for brain metastasis

Jean Zhao

Dana-Farber Cancer Institute

Targeting cancer brain metastasis: insights from mouse models and NGS

Xiang Zhang

Baylor College of Medicine

Novel approaches to model early-stage bone metastases and discover anti-metastasis therapies

Qinghua Zhou

West China Hospital

Translational Medicine of Lung Cancer Metastasis: from bench to bedsides.

Lun-Xiu Qin△

Fudan University

The dysregulation of metabolism and cancer metastasis

Fibrosis-molecular mechanisms and future therapeutics

Youhua Liu△

University of Pittsburgh Medical Center

Molecular mechanisms of renal fibrosis

Jingwu Xie△*

Indiana University School of Medicine

Is hedgehog signaling critical for pathological fibrosis?

Dianhua Jiang

Cedars Sinai Medical Center

TLR4, HA and lung stem cells in lung injury, repair and fibrosis

Ivana V. Yang

University of Colorado Denver

Epigenetic regulation of pulmonary fibrosis

LAN Hui Yao

Prince of Wales Hospital

TGFbeta/SMAD signaling and fibrosis

Drug Discovery & Biomarkers

Xiao-Yan Wen△*

University of Toronto

Zebrafish based chemical genetic screens for drug development

Heyu Ni△

Keenan Research Centre

Novel mechanisms and targets of thrombosis: Development of new drugs targeting platelet adhesion molecules

Peter Liu

University of Ottawa Heart Institute

Insight into Novel Mechanisms of Heart Failure through Proteomic Biomarker Search

Yibin Feng

The University of Hong Kong

Drug discovery from Chinese medicines: the past, present and future

Xiaoliang Wang

Institute of Materia Medica, CAMS

Translational study of biomarkers and drug targets for neurodegenerative diseases

Mucosal Immunity and Associated Diseases

Chen Dong△

Tsinghua University

 

Xin Lin

Tsinghua University

 

Pentao Liu

Sanger Institute, Cambridge

 

Min Li

Memorial Sloan-Kettering Cancer Center

 

Bing Su△*

Shanghai Institute of Immunology/Yale University

 

Neurodevelopment and disorders

Shen-Ju Chou

Institute of Cellular and Organismic Biology, Academia Sinica

COUP-TF1 regulates cortical regional patterning

Zheng Li

NIH

The function of the schizophrenia risk gene DTNBP1 in synapse development and neural
oscillation

Hui-Chen Lu

Indiana University

Mouse model for studying FGFR3 mutation in human thanatophoric dysplasia

Yi-Ping Hsueh△*

Institute of Molecular Biology, Academia Sinica

Using Mouse Models to Assess Developmental Deficits in Neurological Disorders

Jun Xia

Hong Kong University of Science and Technology

Role of PICK1 in protein trafficking and diseases

Transcription Mechanisms and Human Diseases

Haitao Li

Tsinghua University

Sensing Histone Crotonylation for Transcription Control

Gang Wang

Inst of Biochem & Cell Biol, CAS

Mediator-ing Transcription and Cell Fates

Qiang Wu

Shanghai Jiao Tong University

Protocadherin Gene Regulation in Development and Diseases

Jiemin Wong△

East China Normal University

Control of Global Transcription via CDK9 Sumoylation and MYC

Cheng-Ming Chiang△*

UT Southwestern Medical Center

BRD4 in Transcription Programming and Cancer Therapy

Human iPSC-based modeling of neurodevelopment and diseases

Yanhong Shi△*

City of Hope

Studying neurological diseases using patient iPSC models

Yadong Huang△

Gladstone Institute of Neurological Disease

Modeling Alzheimer’s disease and drug screening using human iPSCs

Su-Chun Zhang

University of Wisconsin

Reconstruction of neural circuits by human stem cells

Zhexing Wen

Emory University School of Medicine

Modeling Zika virus exposure with human iPSC-derived neural cells

Chun-Li Zhang

UT Southwestern Medical Center

Direct neural reprogramming for modeling human motor neuron disease

Frontiers of Liver Cancer Research

Hongyang Wang

Eastern Hepatobiliary Surgery Hospital

Molecular pathogenesis of liver cancer

Xin Wei Wang△*

National Cancer Institute

Liver cancer genome and biology

Juling Ji

Natong Medical University

Hepatic stellate cells and liver cancer

Junfang Ji△*

Zhejiang University

Roles of microRNAs in liver cancer stem cells

Bin Zhao

Zhejiang University Life Sciences Institute

YAP pathway and liver cancer

Epigenetics and Hamatological Malignancies

Mingjiang Xu△*

University of Miami Miller School of Medicine

 

Jianjun Chen△*

University of Cincinnati College of Medicine

 

Suming Huang

University of Florida College of Medicine

The role of CTCF in 3D genome organization and leukemogenesis

Feng-Chun Yang

University of Miami Miller School of Medicine

Mutations of ASXL1/2 in myeloid malignancies

Xinyang Zhao

The University of Alabama at Birmingham

Epigenetic impacts of PRMT1-mediated metabolic reprogramming in megakaryopoiesis

Zhijian Qian

University of Illinois at Chicago

The role of EVI1-induced aberrant methylation in AML

Jia Yu

Institute of Basic Medical Sciences, CAMS

The regulation of microRNA biogenesis in erythropoiesis and acute erythroid leukemia

Cure of Chronic Viral Hepatitis

James Jing-Hsiung Ou△

USC Keck School of Medicine

 

Guangxiang (George) Luo△*

University of Alabama at Birmingham

Model systems for the study of hepatitis viruses and antiviral drug discovery

Jianming Hu,

Penn State College of Medicien

HBV Capsid as Regulator of cccDNA Formation and Target for Viral Clearance

Wenhui Li,

National Institute of Biological Sciences

NTCP as a HBV Entry receptor

Jianhua Sui,

National Institute of Biological Sciences

Human Monoclonal Antibodies against HBV and Mechanisms of Action.

Haitao Guo,

Indiana University

HBV cccDNA: how is it made? how to destroy it?

Liver Cancer : Prognostic Biomarkers, Surveillance and Prevention

Fung-Lung Chung△*

Georgetown University

 

Hongyang Wang

Shanghai Jiao
Tong University

 

Eiji Hara

Japanese Foundation for Cancer Research

Oxidiative stress and d-Rom is predicting liver cancer recurrence.

Ying Fu△

Center for Cancer Research, NCI

An endogenous DNA adduct as a biomarker for liver cancer and it is prevention by antioxidants

Ke Zen/Chen-Yu Zhang

Nanjing University

microRNAs as biomarkers for liver cancer Prognosis/diagnosis.

王鐘貴

台北市聯合醫院

 

Function and mechanism of Hedgehog signaling in development and diseases

Steven Y Cheng△

Nanjing Medical University

The Yins and Yangs of Suppressor of fused in Hedgehog signaling

Jin Jiang△

UT Southwestern Medical Center at Dallas

 

Jingwu Xie

Indiana University School of Medicine

Hedgehog signaling in the metastatic niche

Aiming Liu

The Pennsylvania State University

Spop positively regulates Ihh signaling in mammalian skeletal development

Yun Zhao

Institute of Biochemistry and Cell Biology, CAS

 

Blood cell research and treatment: leading precision & regenerative medicine again in the
next decade

He Huang△*

Zhejiang University School of Medicine

BMT and CAR-T therapies for ALL and other blood diseases

Linzhao Cheng△

Johns Hopkins Medicine

Massive productive red blood cells from human stem cells for precise cell therapy

Tao Cheng

Institute of Hematology, CAS

Tackling blood cancer with stem cell approaches

Jianfeng Zhou,

Tongji Medical School in HUST

EBV-associated Lymphoproliferative diseases: Mechanism and Actions

Wei Li Zhao

Shanghai Rui-Jin Hospital

 

Recombinant fusion proteins as novel therapeutics

Wei-Chiang Shen △*

University of Southern California School of Pharmacy

Single-chain Fc dimer fusion proteins

Jeffrey Wang△

Western University of Health Sciences College of Pharmacy

Transferrin-Factor IV Fusion Protein as Novel Therapeutics for Hemophilia B

Li-Jiuan Shen

National Taiwan University School of Pharmacy

Therapeutic fusion proteins of pH-sensitive cell penetrating peptides for selective delivery to
hypoxic cancer cells

Chunmeng Sun

China Pharmaceutical University

recombinant oligopeptides for tumor-targeted delivery of macromolecule and nanocarriers

Jeffrey Lu

AskGene Pharmaceuticals

Preclinical and clinical development for innovative fusion protein molecules: case studies

Regulatory T cells in cancers and autoimmune diseases

Weiping Zou△*

University of Michigan Health System

Tregs and cancer immunotherapy

Guangyong Peng

Saint Louis University University

T cells in Tumor microe, nviroment

Yuncai Liu

Tsinghua University

Tregs and Itch

Lingyun Sun

Nanjing Medical University

MSCs and Tregs in SLE

Wanjun Chen△*

National Institutes of Health

Generation and function of Tregs

Genomic and functional studies of human leukemia

Paul Liu△

NHGRI, NIH

 

Ruibao Ren△

Brandeis University and Shanghai Institute of Hematology

 

Dong-Er Zhang

UC San Diego

 

Saijuan Chen

Shanghai Institute of Hematology

 

Shaoguang Li

University of Massachusetts Medical School

Strategies for targeting leukemia stem cells: lessons learned from CML biology

Tao Cheng

CAMS Institute of Hematology in Tianjin

 

Jing Zhang

University of Wisconsin

Ras-driven leukemias: mechanisms and potential therapeutics

Paradoxical TGF‐beta Signaling in Development, Diseases and Therapeutics

Xin-Hua FENG △*

Zhejiang University

 

Xiao-Fan Wang

Duke University School of Medicine

Cellular senescence and TGF-beta signaling

Ying E Zhang

National Cancer Institute, NIH

Context-dependent regulation of alternative splicing by TGF-b

Xiao Yang

Institute of Biotechnology

TGF-b signaling in cardiac hypertrophy

Xiao-Jing Wang△

University of Colorado Anschutz Medical Campus

Therapeutic roles of TGF-b inhibition in cancer treatment and care

Ubiquitin signaling in inflammation and cancer

Shao-Cong Sun△

University of Texas MD Anderson Cancer
Center

Ubiquitin signaling in the regulation of inflammation and
anti-tumor immunity.

Hui-Kuan Lin△

Comprehensive Cancer Center, Wake
Forest School of Medicine

Histone ubiquitination regulates hypoxia signaling and
cancer metastasis

Jianping Jin

University of Texas
Health Science Center at Houston

Ubiquitin and ubiquitin-like proteins in inflammation
control

Ruey-Hwa Chen

Institute of Biological Chemistry, Academia Sinica

Ubiquitination in Tumor Promotion and Autophagy
Regulation

Yong Wan

University of Pittsburgh

Post-translational modification in genome stability and
carcinogenesis

Metabolic Targets for Cancer Therapy

Deliang Guo△*

The Ohio State University James Comprehensive Cancer Center
and College of Medicine

SCAP/SREBP-1, Central Regulators of Lipid Metabolism Reprogramming and Promising Targets in Cancer

Zhang Weihua△

University of Houston

Targeting Metabolisms Controlled by EGFR’s Kinase Independent Functions for Cancer Therapy

Qing Zhang

UNC-Chapel Hill

The Oxygen Sensor EglN2 Serves as a New Metabolic Target in Breast Cancer

Ming Tan

U of South Alabama

Inhibiting Dysregulated LDHA and PDK1 to Overcome HER2-targeting Resistance in
Breast Cancer

Jinke Cheng

Shanghai Jiao Tong University School of Medicine

SUMOylation Regulates Mitochondrial Metabolism in Tumorigenesis

Stem cells: engineering and disease modeling

Chuxia Deng△*

University of Macau

Transcriptome analysis of mammary stem cells and cancer stem cells

Ren-He Xu△*

University of Macau

3D, a game changer for hESC and progeny

Linzhao Cheng

Johns Hopkins University School of Medicine

Human iPS cells and genome editing for blood disease modeling and treatment

Yufang Shi

Soochow University Institute for Translational Medicine

Mesenchymal stem cells and tissue microenvironment

Junying Yu

NuwaCell.Ltd

Hematopoietic programming

Mechanisms and therapy of neurodegenerative diseases

Hui Zheng△*

Baylor College of Medicine

The autophagy and lysosomal pathway in Alzheimer’s disease

Hong Lian△

Zhejiang University School of Medicine

The role of complement receptor C3aR in synaptic dysfunction in excitotoxicity

Yueming Li

Memorial Sloan Kettering Cancer Center

Modulation of γ-Secretase

Sheng Zhang

The University of Texas Health Science Center at Houston

Selective Macroautophagy in Huntington’s disease

Riqiang Yan

Cleveland Clinic Learner Research Institute

Inhibition of BACE1 of benefiting Alzheimer’s patients.

Biomotors, single-pore sensing and RNA nanotechnology

Liqun Gu△*

University of Missouri,

Nanopore force toolbox: from mechanistic study of molecular folding/unfolding to clinical
detection of biomarkers

Jia Geng

Sichuan University

Biological and artificial nanopores for single molecule sensing

Haichen Wu

Institute of High Energy Physics

Sensing of DNA damages with protein nanopore

Peixuan Guo△*

The Ohio State University

Arginine finger regulates the sequential action of asymmetrical hexameric nanopore for single
direction DNA translocation

Zhengyi Zhao

Huazhong University of Science and Technology

Arginine finger coordinates the sequential action of asymmetrical hexameric ATPase for single direction DNA translocation

Cell death and inflammasome signaling in normal physiology and diseases

Jianke Zhang△*

Thomas Jefferson University

Apoptosis and necroptosis in immune homeostasis

Jiahui Han△

Xiamen University

Inflammasome signaling

Emad Elnemri

Thomas Jefferson University

Pyroptosis signaling

Zhenggang Liu

NCI/NIH

Cell death and caner

Francis Chan

University of Massachusetts

Cell death in colitis

liming.sun

Shanghai Institutes of Biological Sciences

Cell death signaling through MLKL

Neural development and related diseases

Jia-Wei Zhou

Institute of Neuroscience, SIBS, CAS

Role of NG2 glial cells in neuroinflammation

Zhiheng Xu△

Instituteof Genetics & Developmental Biology, CAS

Zika Virus infection and Microcephaly: Mechanism and Treatment

Yongchun Yu

Fudan University

Fear erasure facilitated by immature inhibitory neuron transplantation

Yufang Zheng

Fudan University

MiR-197 rescues the neurogenesis defects caused by autistic MECP2 mutations

 Zhen-Ge Luo△*

Institute of Neuroscience, SIBS, CAS

Identification of a novel axon guidance factor expressed in Cajal-Retzius cells

Synaptic  plasticity  (tentative  topic,  will  be  slightly  modified  after  knowing  every  speaker’s presentation title)

Yi-Shuian Huang△*（黄怡萱）

Institute of Biomedical Sciences, Academia Sinica

CPEB-controlled translation and plasticity

Yingxi Lin (林映晞)

Massachusetts Institute of Technology

Transcribing Memories

Xiao-hui Zhang

Beijing Normal University

Cortical circuitry mechanisms underlying the critical period plasticity

Eminy Lee （李小媛）

Institute of Biomedical Sciences, Academia Sinica

Galectin-3 is a novel negative regulator of memory formation

Chia-Lin Wu (吳嘉霖)

Chang Gung University

Neural circuits for long-term water-reward memory processing in Drosophila

Mechanisms of embryogenesis and organogenesis

Naihe Jing△*

Shanghai Institute of Biochemistry and Cell Biology

Spatial and temporal transcriptome of early mouse embryos

Chi-chung Hui△*

The Hospital for Sick Children

Gene regulatory network in cerebellum development and tumorigenesis

Jian Zhang

Institute of Genetics and Developmental Biology, CAS

Translation regulation of maternal RNAs in zebrafish

Ping Hu

Shanghai Institute of Biochemistry and Cell Biology

Balance of RNA binding proteins regulates myogenesis

Bo Gao

The University of Hong Kong

Wnt regulation of Planar Cell Polarity

Wnt signaling in development, stem cells, and cancer

Xi He△*

Boston Children’s Hospital/Harvard Medical School

Wnt signaling in development and stem cells

Yi Arial Zeng△

Institute of Biochemistry and Cell Biology, CAS

Wnt signaling in regulating mammary stem cell and breast cancer

Xinhua Lin

Fudan University

Regulation of intestinal patterning and homeostasis by Wnt signaling

Dianqing (Dan) Wu

Yale School of Medicine

Wnt signaling in cancer.

Ting Chen

National Institute of Biological Sciences，Beijing

Dynamic change in Wnt signaling establishes hair follicle stem cell niche

Neural circuit of behavior

Hailan Hu△

Zhejiang University School of medicine

Neural mechanism of emotion

Yutian Wang

The University of British Columbia

AMPAR trafficking in synaptic plasticity, learning and memory

Xiaomin Li

Zhejiang University School of medicine

Cholinergic regulation of GABAergic neurons

Minmin Luo

National Institute of Biological Sciences，Beijing

Neural circuits for reward

Hao Wang△

Zhejiang University School of medicine

Midbrain GABAergic pathways for feeding behavior

Xiaowei Chen

Third Military Medical University

Two-­‐photon calcium imaging of sensory cortex circuits during a simple learning

Precision Medicine-Gene Based Therapy

Jim Hu△*

Hospital for Sick Children

Spatial and temporal transcriptome of early mouse embryos

Xiao Xiao △*

UNC Eshelman School of Pharmacy

Muscle as a platform for gene therapy

Weidong Xiao

Temple University

Optimization of clotting factor VIII for hemophilia A gene therapy

Zhijian Wu

National Institutes of Health

Gene replacement therapy for X-Linked Retinitis Pigmentosa (XLRP)

Yichang Jia

Tsinghua University

Discovery and Gene Repair for Neurodegenerative Diseases

Immunotherapy

Dongfang Liu

Houston Methodist Research Institute

CAR-NK Immunotherapy for Infectious Diseases

Yi Zhang

Zhengzhou University

Dissecting Tumor Microenvironment for Treatment of Cancer

Jianhua Yu

The Ohio State University

Natural Killer Cell Biology and Immunotherapy

Rongfu Wang△

Houston Methodist Research Institute

Cancer Immunotherapy

Wei-dong Han△

Chinese PLA General Hospita

CAR T therapy in liquid and solid tumors